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Multidrug Resistance Conferred by Novel DNA Polymerase Mutations in Human Cytomegalovirus Isolates

The emergence of antiviral-resistant cytomegalovirus (CMV) strains is a continuing clinical problem, with increased numbers of immunocompromised patients given longer-duration antiviral prophylaxis. Two previously unrecognized CMV DNA polymerase mutations (N408K and A834P) identified separately and...

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Main Authors: Scott, Gillian M., Weinberg, Adriana, Rawlinson, William D., Chou, Sunwen
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797699/
https://ncbi.nlm.nih.gov/pubmed/17043128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00633-06
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