Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenes

Studies of the human pathogen group A Streptococcus (GAS) define the carrier phenotype to be an increased ability to adhere to and persist on epithelial surfaces and a decreased ability to cause disease. We tested the hypothesis that a single amino acid change (Arg135Gly) in a highly conserved senso...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Flores, Anthony R., Olsen, Randall J., Cantu, Concepcion, Pallister, Kyler B., Guerra, Fermin E., Voyich, Jovanka M., Musser, James M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400840/
https://ncbi.nlm.nih.gov/pubmed/28264907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00949-16
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