Stable and potent selenomab-drug conjugates

Selenomabs are engineered monoclonal antibodies with one or more translationally incorporated selenocysteine residues. The unique reactivity of the selenol group of selenocysteine permits site-specific conjugation of drugs. Compared to other natural and unnatural amino acid and carbohydrate residues...

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Détails bibliographiques
Publié dans:Cell Chem Biol
Auteurs principaux: Li, Xiuling, Nelson, Christopher G., Nair, Rajesh R., Hazlehurst, Lori, Moroni, Tina, Martinez-Acedo, Pablo, Nanna, Alex R., Hymel, David, Burke, Terrence R., Rader, Christoph
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400723/
https://ncbi.nlm.nih.gov/pubmed/28330604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.02.012
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