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Chronic Oral Methylphenidate Treatment Reversibly Increases Striatal Dopamine Transporter and Dopamine Type 1 Receptor Binding in Rats
Previously, we created an eight hour limited-access dual bottle drinking paradigm to deliver methylphenidate (MP) to rats at two dosages that result in a pharmacokinetic profile similar to patients treated for Attention Deficit Hyperactivity Disorder. Chronic treatment resulted in altered behavior,...
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| Udgivet i: | J Neural Transm (Vienna) |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400672/ https://ncbi.nlm.nih.gov/pubmed/28116523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-017-1680-4 |
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