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A pharmacokinetic model of oral methylphenidate in the rat and effects on behavior
Most animal studies using methylphenidate (MP) do not administer it the same way it is administered clinically (orally), but rather by injection, resulting in an altered pharmacokinetic profile (i.e. quicker and higher peak concentrations). Here, we evaluated several oral-dosing regimens in rats, in...
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Publicado no: | Pharmacol Biochem Behav |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461871/ https://ncbi.nlm.nih.gov/pubmed/25641666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2015.01.005 |
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