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ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

The efficacy of Ataxia-Telangiectasia Mutated (ATM) kinase signalling inhibition in cancer therapy is tempered by the identification of new emerging functions of ATM, which suggests that the role of this protein in cancer progression is complex. We recently demonstrated that this tumor suppressor ge...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Antonelli, Martina, Strappazzon, Flavie, Arisi, Ivan, Brandi, Rossella, D’Onofrio, Mara, Sambucci, Manolo, Manic, Gwenola, Vitale, Ilio, Barilà, Daniela, Stagni, Venturina
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400616/
https://ncbi.nlm.nih.gov/pubmed/28423511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15537
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