Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma

Histone H3 lysine 9 dimethylation (H3K9me2) is mainly regulated by the histone lysine methyltransferase G9a and is associated with the repression of transcription. However, both the role of G9a and the significance of H3K9me2 in hepatocellular carcinoma (HCC) cells remain unclear. In this study, we...

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Opis bibliograficzny
Wydane w:Oncotarget
Główni autorzy: Yokoyama, Masayuki, Chiba, Tetsuhiro, Zen, Yoh, Oshima, Motohiko, Kusakabe, Yuko, Noguchi, Yoshiko, Yuki, Kaori, Koide, Shuhei, Tara, Shiro, Saraya, Atsunori, Aoyama, Kazumasa, Mimura, Naoya, Miyagi, Satoru, Inoue, Masanori, Wakamatsu, Toru, Saito, Tomoko, Ogasawara, Sadahisa, Suzuki, Eiichiro, Ooka, Yoshihiko, Tawada, Akinobu, Otsuka, Masayuki, Miyazaki, Masaru, Yokosuka, Osamu, Iwama, Atsushi
Format: Artigo
Język:Inglês
Wydane: Impact Journals LLC 2017
Hasła przedmiotowe:
Research Paper
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400586/
https://ncbi.nlm.nih.gov/pubmed/28423509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15528
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