Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

Cisplatin chemotherapy often causes acute kidney injury (AKI) in cancer patients. There is increasing evidence that mitochondrial dysfunction plays an important role in cisplatin-induced nephrotoxicity. Degradation of damaged mitochondria is carried out by mitophagy. Although mitophagy is considered...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhao, Chuanyan, Chen, Zhuyun, Qi, Jia, Duan, Suyan, Huang, Zhimin, Zhang, Chengning, Wu, Lin, Zeng, Ming, Zhang, Bo, Wang, Ningning, Mao, Huijuan, Zhang, Aihua, Xing, Changying, Yuan, Yanggang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400560/
https://ncbi.nlm.nih.gov/pubmed/28423497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15470
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