Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

Cisplatin chemotherapy often causes acute kidney injury (AKI) in cancer patients. There is increasing evidence that mitochondrial dysfunction plays an important role in cisplatin-induced nephrotoxicity. Degradation of damaged mitochondria is carried out by mitophagy. Although mitophagy is considered...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Zhao, Chuanyan, Chen, Zhuyun, Qi, Jia, Duan, Suyan, Huang, Zhimin, Zhang, Chengning, Wu, Lin, Zeng, Ming, Zhang, Bo, Wang, Ningning, Mao, Huijuan, Zhang, Aihua, Xing, Changying, Yuan, Yanggang
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400560/
https://ncbi.nlm.nih.gov/pubmed/28423497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15470
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