Design, sythesis and evaluation of a series of 3- or 4-alkoxy substituted phenoxy derivatives as PPARs agonists

Peroxisome proliferators-activated receptors (PPARα, γ and δ) are potentially effective targets for Type 2 diabetes mellitus therapy. The severe effects of known glitazones and the successfully approved agents (saroglitazar and lobeglitazone) motivated us to study novelly potent PPARs drugs with imp...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Zhang, Jun, Wang, Xue-Jiao, Liu, Xin, Huan, Yi, Yang, Miao-Miao, Shen, Zhu-Fang, Jia, Wen-Qing, Jing, Zhi, Wang, Shu-Qing, Xu, Wei-Ren, Cheng, Xian-Chao, Wang, Run-Ling
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400543/
https://ncbi.nlm.nih.gov/pubmed/28186999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15198
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