The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors

Genetic and environmental factors, such as metals, interact to determine neurological traits. We reasoned that interactomes of molecules handling metals in neurons should include novel metal homeostasis pathways. We focused on copper and its transporter ATP7A because ATP7A null mutations cause neuro...

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Publicado no:eLife
Main Authors: Comstra, Heather S, McArthy, Jacob, Rudin-Rush, Samantha, Hartwig, Cortnie, Gokhale, Avanti, Zlatic, Stephanie A, Blackburn, Jessica B, Werner, Erica, Petris, Michael, D’Souza, Priya, Panuwet, Parinya, Barr, Dana Boyd, Lupashin, Vladimir, Vrailas-Mortimer, Alysia, Faundez, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400511/
https://ncbi.nlm.nih.gov/pubmed/28355134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24722
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