The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors

Genetic and environmental factors, such as metals, interact to determine neurological traits. We reasoned that interactomes of molecules handling metals in neurons should include novel metal homeostasis pathways. We focused on copper and its transporter ATP7A because ATP7A null mutations cause neuro...

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Pubblicato in:eLife
Autori principali: Comstra, Heather S, McArthy, Jacob, Rudin-Rush, Samantha, Hartwig, Cortnie, Gokhale, Avanti, Zlatic, Stephanie A, Blackburn, Jessica B, Werner, Erica, Petris, Michael, D’Souza, Priya, Panuwet, Parinya, Barr, Dana Boyd, Lupashin, Vladimir, Vrailas-Mortimer, Alysia, Faundez, Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400511/
https://ncbi.nlm.nih.gov/pubmed/28355134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24722
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