NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity

Animal studies have shown that the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus can activate the thiazide-sensitive NaCl cotransporter (NCC). A common side effect of CNIs is hypertension. Renal salt transporters such as NCC are excreted in urinary extracellular vesicles (uEVs) after int...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tutakhel, Omar A. Z., Moes, Arthur D., Valdez-Flores, Marco A., Kortenoeven, Marleen L. A., Vrie, Mathijs v. D., Jeleń, Sabina, Fenton, Robert A., Zietse, Robert, Hoenderop, Joost G. J., Hoorn, Ewout J., Hilbrands, Luuk, Bindels, René J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400280/
https://ncbi.nlm.nih.gov/pubmed/28430812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176220
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados