Ultrasensitivity and heavy-metal selectivity of the allosterically modulated MerR transcription complex.

The MerR metalloregulatory protein is a heavy-metal receptor that functions as the repressor and Hg(II)-responsive transcription activator of the prokaryotic mercury-resistance (mer) genes. We demonstrate that this allosterically modulated regulatory protein is sensitive to HgCl2 concentrations of 1...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ralston, D M, O'Halloran, T V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2187194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3846
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