Ultrasensitivity and heavy-metal selectivity of the allosterically modulated MerR transcription complex.
The MerR metalloregulatory protein is a heavy-metal receptor that functions as the repressor and Hg(II)-responsive transcription activator of the prokaryotic mercury-resistance (mer) genes. We demonstrate that this allosterically modulated regulatory protein is sensitive to HgCl2 concentrations of 1...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1990
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2187194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3846 |
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