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Effects of CYP2D6 and CYP3A5 polymorphisms on tamoxifen and its metabolites in Thai breast cancer patients

PURPOSE: This study aimed to determine the effects of CYP2D6 and CYP3A5 polymorphisms on the levels of tamoxifen (TAM) and its metabolites in the plasma of breast cancer patients. The protocol was designed to test the associations between CYP2D6, CYP3A5 genotypes and phenotypes (extensive metabolize...

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Detalhes bibliográficos
Publicado no:Breast Cancer (Dove Med Press)
Main Authors: Charoenchokthavee, Wanaporn, Areepium, Nutthada, Panomvana, Duangchit, Sriuranpong, Virote
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399972/
https://ncbi.nlm.nih.gov/pubmed/28450788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S125745
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