CYP2D6 polymorphisms influence the efficacy of adjuvant tamoxifen in Thai breast cancer patients

AIM: We evaluated single nucleotide polymorphisms (SNPs) of CYP2D6 to identify those that influence the efficiency of tamoxifen in adjuvant treatment of breast cancer through a matched case–control study. METHODS: Peripheral blood DNA was collected from 20 patients with disease recurrence during adj...

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Détails bibliographiques
Auteurs principaux: Sirachainan, Ekaphop, Jaruhathai, Sureerat, Trachu, Narumol, Panvichian, Ravat, Sirisinha, Thitiya, Ativitavas, Touch, Ratanatharathorn, Vorachai, Chamnanphon, Montri, Sukasem, Chonlaphat
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2012
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513236/
https://ncbi.nlm.nih.gov/pubmed/23226070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S32160
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