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Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16.

The gene for human high-mobility-group (HMG) chromosomal protein HMG-14 is located in region 21q22.3, a region associated with the pathogenesis of Down syndrome, one of the most prevalent human birth defects. The expression of this gene is analyzed in mouse embryos that are trisomic in chromosome 16...

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Bibliographic Details
Main Authors: Pash, J, Popescu, N, Matocha, M, Rapoport, S, Bustin, M
Format: Artigo
Language:Inglês
Published: 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53998/
https://ncbi.nlm.nih.gov/pubmed/2140193
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