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Bardoxolone Methyl and a Related Triterpenoid Downregulate cMyc Expression in Leukemia Cells
Structurally related pentacyclic triterpenoids methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate [bardoxolone-methyl (Bar-Me)] and methyl 2-trifluoromethyl-3,11-dioxoolean-1,12-dien-30-oate (CF(3)DODA-Me) contain 2-cyano-1-en-3-one and 2-trifluoromethyl-1-en-3-one moieties, respectively, in their A-ri...
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| Publicado en: | Mol Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399643/ https://ncbi.nlm.nih.gov/pubmed/28275049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106245 |
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