Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites

Enhancers frequently contain multiple binding sites for the same transcription factor. These homotypic binding sites often exhibit synergy, whereby the transcriptional output from two or more binding sites is greater than the sum of the contributions of the individual binding sites alone. Although t...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Anderson, Courtney M., Hu, Jianxin, Thomas, Reuben, Gainous, T. Blair, Celona, Barbara, Sinha, Tanvi, Dickel, Diane E., Heidt, Analeah B., Xu, Shan-Mei, Bruneau, Benoit G., Pollard, Katherine S., Pennacchio, Len A., Black, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399617/
https://ncbi.nlm.nih.gov/pubmed/28351867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138487
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