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Mouse models of MLL leukemia: recapitulating the human disease
Chromosome translocations involving the mixed lineage leukemia (MLL) gene fuse it in frame with multiple partner genes creating novel fusion proteins (MLL-FPs) that cause aggressive acute leukemias in humans. Animal models of human disease are important for the exploration of underlying disease mech...
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| Veröffentlicht in: | Blood |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399479/ https://ncbi.nlm.nih.gov/pubmed/28179274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-691428 |
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