A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines

Since 1997, highly pathogenic avian influenza viruses of the H5N1 subtype have been transmitted from avian hosts to humans. The severity of H5N1 infection in humans, as well as the sporadic nature of H5N1 outbreaks, both geographically and temporally, make generation of an effective vaccine a global...

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Publicado en:Sci Rep
Main Authors: Van Hoeven, Neal, Fox, Christopher B., Granger, Brian, Evers, Tara, Joshi, Sharvari W., Nana, Ghislain I., Evans, Sarah C., Lin, Susan, Liang, Hong, Liang, Li, Nakajima, Rie, Felgner, Philip L., Bowen, Richard A., Marlenee, Nicole, Hartwig, Airn, Baldwin, Susan L., Coler, Rhea N., Tomai, Mark, Elvecrog, James, Reed, Steven G., Carter, Darrick
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399443/
https://ncbi.nlm.nih.gov/pubmed/28429728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46426
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