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Pharmacological inhibition of spinal cord injury-stimulated ribosomal biogenesis does not affect locomotor outcome

After unresolved endoplasmic reticulum stress, recovery of protein synthesis including increased expression of ribosomal components and translation factors may induce cell death. Using a mouse model of moderate contusive spinal cord injury (SCI) at the T9 level, upregulation of ribosomal biogenesis...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Kilanczyk, Ewa, Andres, Kariena R., Hallgren, Justin, Ohri, Sujata Saraswat, Laiho, Marikki, Whittemore, Scott R., Hetman, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399421/
https://ncbi.nlm.nih.gov/pubmed/28188847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2017.02.011
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