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Antioxidant Protection of NADPH-Depleted Oligodendrocyte Precursor Cells Is Dependent on Supply of Reduced Glutathione

The pentose phosphate pathway is the main source of NADPH, which by reducing oxidized glutathione, contributes to antioxidant defenses. Although oxidative stress plays a major role in white matter injury, significance of NADPH for oligodendrocyte survival has not been yet investigated. It is reporte...

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Dettagli Bibliografici
Pubblicato in:ASN Neuro
Autori principali: Kilanczyk, Ewa, Saraswat Ohri, Sujata, Whittemore, Scott R., Hetman, Michal
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962338/
https://ncbi.nlm.nih.gov/pubmed/27449129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091416660404
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