Neutrophil stunning by metoprolol reduces infarct size

The β1-adrenergic-receptor (ADRB1) antagonist metoprolol reduces infarct size in acute myocardial infarction (AMI) patients. The prevailing view has been that metoprolol acts mainly on cardiomyocytes. Here, we demonstrate that metoprolol reduces reperfusion injury by targeting the haematopoietic com...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: García-Prieto, Jaime, Villena-Gutiérrez, Rocío, Gómez, Mónica, Bernardo, Esther, Pun-García, Andrés, García-Lunar, Inés, Crainiciuc, Georgiana, Fernández-Jiménez, Rodrigo, Sreeramkumar, Vinatha, Bourio-Martínez, Rafael, García-Ruiz, José M, del Valle, Alfonso Serrano, Sanz-Rosa, David, Pizarro, Gonzalo, Fernández-Ortiz, Antonio, Hidalgo, Andrés, Fuster, Valentín, Ibanez, Borja
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399300/
https://ncbi.nlm.nih.gov/pubmed/28416795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14780
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