Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity

Serotonin (5-HT) deficiency occurs in a number of brain disorders that affect cognitive function. However, a direct causal relationship between 5-HT hypo-transmission and memory and underlying mechanisms has not been established. We used mice with a constitutive depletion of 5-HT brain levels (Pet1K...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Fernandez, Sebastian P, Muzerelle, Aude, Scotto-Lomassese, Sophie, Barik, Jacques, Gruart, Agnès, Delgado-García, José M, Gaspar, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399229/
https://ncbi.nlm.nih.gov/pubmed/27461084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.134
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