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Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity

Serotonin (5-HT) deficiency occurs in a number of brain disorders that affect cognitive function. However, a direct causal relationship between 5-HT hypo-transmission and memory and underlying mechanisms has not been established. We used mice with a constitutive depletion of 5-HT brain levels (Pet1K...

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Bibliografiske detaljer
Udgivet i:Neuropsychopharmacology
Main Authors: Fernandez, Sebastian P, Muzerelle, Aude, Scotto-Lomassese, Sophie, Barik, Jacques, Gruart, Agnès, Delgado-García, José M, Gaspar, Patricia
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399229/
https://ncbi.nlm.nih.gov/pubmed/27461084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.134
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