Trans-dominant negative mutants of Fos and Jun.

Jun and Fos nuclear oncoproteins form a complex that regulates transcription from promoters containing activator protein AP-1 binding sites. The leucine-zipper and basic-region domains of both Fos and Jun are necessary for formation of the heterodimer that binds to DNA. Reciprocal mutations in the b...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ransone, L J, Visvader, J, Wamsley, P, Verma, I M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2111017/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3806
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