AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal

Dedifferentiation and degeneration of chondrocytes critically influences the efficiency of cartilage repair. One of the causes is the defect of transforming growth factor (TGF)-β signaling that promotes chondrogenic differentiation and degeneration. In the present study, we found that aminoacyl-tRNA...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ahn, J, Kumar, H, Cha, B-H, Park, S, Arai, Y, Han, I, Park, S G, Lee, S-H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399188/
https://ncbi.nlm.nih.gov/pubmed/26890138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.17
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