Calcitonin attenuates cartilage degeneration and nociception in an experimental rat model of osteoarthritis: role of TGF-β in chondrocytes

We investigated the role of the calcitonin (Miacalcin) in the progression of osteoarthritis (OA) and in nociceptive behavior in an experimental rat model of OA and osteoporosis. OA was induced by anterior cruciate ligament transection (ACLT) of the right knee and by bilateral ovariectomy (OVX) in Wi...

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Pubblicato in:Sci Rep
Autori principali: Wen, Zhi-Hong, Tang, Chi-Chieh, Chang, Yi-Chen, Huang, Shi-Ying, Lin, Yen-You, Hsieh, Shih-Peng, Lee, Hsin-Pai, Lin, Sung-Chun, Chen, Wu-Fu, Jean, Yen-Hsuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921823/
https://ncbi.nlm.nih.gov/pubmed/27345362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28862
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