Calcitonin attenuates cartilage degeneration and nociception in an experimental rat model of osteoarthritis: role of TGF-β in chondrocytes

We investigated the role of the calcitonin (Miacalcin) in the progression of osteoarthritis (OA) and in nociceptive behavior in an experimental rat model of OA and osteoporosis. OA was induced by anterior cruciate ligament transection (ACLT) of the right knee and by bilateral ovariectomy (OVX) in Wi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wen, Zhi-Hong, Tang, Chi-Chieh, Chang, Yi-Chen, Huang, Shi-Ying, Lin, Yen-You, Hsieh, Shih-Peng, Lee, Hsin-Pai, Lin, Sung-Chun, Chen, Wu-Fu, Jean, Yen-Hsuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921823/
https://ncbi.nlm.nih.gov/pubmed/27345362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28862
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