Evaluation of low doses BPA-induced perturbation of glycemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity

Epidemiologic and experimental studies have associated changes of blood glucose homeostasis to Bisphenol A (BPA) exposure. We took a toxicogenomic approach to investigate the mechanisms of low-dose (1 × 10(−9 )M) BPA toxicity in ex vivo cultures of primary murine pancreatic islets and hepatocytes. T...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Carchia, E, Porreca, I, Almeida, P J, D'Angelo, F, Cuomo, D, Ceccarelli, M, De Felice, M, Mallardo, M, Ambrosino, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399181/
https://ncbi.nlm.nih.gov/pubmed/26512966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.319
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