Pesticide toxicogenomics across scales: in vitro transcriptome predicts mechanisms and outcomes of exposure in vivo

In vitro Omics analysis (i.e. transcriptome) is suggested to predict in vivo toxicity and adverse effects in humans, although the causal link between high-throughput data and effects in vivo is not easily established. Indeed, the chemical-organism interaction can involve processes, such as adaptatio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Porreca, Immacolata, D’Angelo, Fulvio, De Franceschi, Lucia, Mattè, Alessandro, Ceccarelli, Michele, Iolascon, Achille, Zamò, Alberto, Russo, Filomena, Ravo, Maria, Tarallo, Roberta, Scarfò, Marzia, Weisz, Alessandro, De Felice, Mario, Mallardo, Massimo, Ambrosino, Concetta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131489/
https://ncbi.nlm.nih.gov/pubmed/27905518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38131
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