Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma

Current treatment regimens for rhabdomyosarcoma (RMS), the most common pediatric soft tissue cancer, rely on conventional chemotherapy, and although they show clinical benefit, there is a significant risk of adverse side effects and secondary tumors later in life. Therefore, identifying and targetin...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Satheesha, S, Manzella, G, Bovay, A, Casanova, E A, Bode, P K, Belle, R, Feuchtgruber, S, Jaaks, P, Dogan, N, Koscielniak, E, Schäfer, B W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399168/
https://ncbi.nlm.nih.gov/pubmed/26189795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.267
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