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Afadin is localized at cell–cell contact sites in mesangial cells and regulates migratory polarity

In kidney glomeruli, mesangial cells provide structural support to counteract for expansile forces caused by pressure gradients and to regulate the blood flow. Glomerular injury results in proliferation and aberrant migration of mesangial cells, which is the pathological characteristic of mesangial...

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Dettagli Bibliografici
Pubblicato in:Lab Invest
Autori principali: Tsurumi, Haruko, Kurihara, Hidetake, Miura, Kenichiro, Tanego, Atsushi, Ohta, Yasutaka, Igarashi, Takashi, Oka, Akira, Horita, Shigeru, Hattori, Motoshi, Harita, Yutaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399166/
https://ncbi.nlm.nih.gov/pubmed/26568295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.133
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