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Afadin is localized at cell–cell contact sites in mesangial cells and regulates migratory polarity

In kidney glomeruli, mesangial cells provide structural support to counteract for expansile forces caused by pressure gradients and to regulate the blood flow. Glomerular injury results in proliferation and aberrant migration of mesangial cells, which is the pathological characteristic of mesangial...

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Bibliografske podrobnosti
izdano v:Lab Invest
Main Authors: Tsurumi, Haruko, Kurihara, Hidetake, Miura, Kenichiro, Tanego, Atsushi, Ohta, Yasutaka, Igarashi, Takashi, Oka, Akira, Horita, Shigeru, Hattori, Motoshi, Harita, Yutaka
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399166/
https://ncbi.nlm.nih.gov/pubmed/26568295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.133
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