IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection

Single-nucleotide polymorphisms near the interferon lambda 3 (IFNL3) gene predict outcomes to infection and anti-viral treatment in hepatitis C virus (HCV) infection. To identify IFNL3 genotype effects on peripheral blood, we collected phenotype data on 400 patients with genotype 1 chronic hepatitis...

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Vydáno v:Genes Immun
Hlavní autoři: O'Connor, K S, Read, S A, Wang, M, Schibeci, S, Eslam, M, Ong, A, Weltman, M D, Douglas, M W, Mazzola, A, Craxì, A, Petta, S, Stewart, G J, Liddle, C, George, J, Ahlenstiel, G, Booth, D R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399140/
https://ncbi.nlm.nih.gov/pubmed/27307212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2016.27
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