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IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes

BACKGROUND: Lambda interferons (IFNLs) have potent antiviral activity against HCV, and polymorphisms within the IFNL gene cluster near the IFNL3 gene strongly predict spontaneous- and treatment-related HCV infection outcomes. The mechanism(s) linking IFNL polymorphisms and HCV control is currently e...

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Detalhes bibliográficos
Publicado no:Antivir Ther
Main Authors: Kurbanov, Fuat, Kim, Yonghak, Latanich, Rachel, Chaudhari, Pooja, El-Diwany, Ramy, Knabel, Matt, Kandathil, Abraham J, Cameron, Andrew, Cox, Andrea, Jang, Yoon-Young, Thomas, David L, Balagopal, Ashwin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821403/
https://ncbi.nlm.nih.gov/pubmed/26109548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2974
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