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Further characterization of the GlyT-1 inhibitor Org25935: anti-alcohol, neurobehavioral, and gene expression effects

The glycine transporter-1 inhibitor Org25935 is a promising candidate in a treatment concept for alcohol use disorder targeting the glycine system. Org25935 inhibits ethanol-induced dopamine elevation in brain reward regions and reduces ethanol intake in Wistar rats. This study aimed to further char...

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Detalhes bibliográficos
Publicado no:J Neural Transm (Vienna)
Main Authors: Lidö, Helga Höifödt, Jonsson, Susanne, Hyytiä, Petri, Ericson, Mia, Söderpalm, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399095/
https://ncbi.nlm.nih.gov/pubmed/28161754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-017-1685-z
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