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Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1

Molecular chaperones are required to maintain the proteome in a folded and functional state. When challenges to intracellular folding occur, the heat shock response is triggered, leading to increased synthesis of a class of inducible chaperones known as heat shock proteins (HSP). Although HSP synthe...

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Foilsithe in:Front Neurosci
Main Authors: Calderwood, Stuart K., Murshid, Ayesha
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399083/
https://ncbi.nlm.nih.gov/pubmed/28484363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00192
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