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Protein Kinase A Regulates Molecular Chaperone Transcription and Protein Aggregation

Heat shock factor 1 (HSF1) regulates one of the major pathways of protein quality control and is essential for deterrence of protein-folding disorders, particularly in neuronal cells. However, HSF1 activity declines with age, a change that may open the door to progression of neurodegenerative disord...

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Detalhes bibliográficos
Main Authors: Zhang, Yue, Murshid, Ayesha, Prince, Thomas, Calderwood, Stuart K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245242/
https://ncbi.nlm.nih.gov/pubmed/22216146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028950
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