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Protein Kinase A Regulates Molecular Chaperone Transcription and Protein Aggregation
Heat shock factor 1 (HSF1) regulates one of the major pathways of protein quality control and is essential for deterrence of protein-folding disorders, particularly in neuronal cells. However, HSF1 activity declines with age, a change that may open the door to progression of neurodegenerative disord...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245242/ https://ncbi.nlm.nih.gov/pubmed/22216146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028950 |
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