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RETRACTED ARTICLE: Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters

Prion infections of the central nervous system (CNS) are characterized by initial reactive gliosis followed by overt neuronal death. Gliosis is likely to be caused initially by the deposition of misfolded, proteinase K-resistant, isoforms (termed PrP(Sc)) of the normal cellular prion protein (PrP(c)...

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Bibliografiset tiedot
Julkaisussa:Neurotherapeutics
Päätekijät: Shah, Syed Zahid Ali, Zhao, Deming, Taglialatela, Giulio, Khan, Sher Hayat, Hussain, Tariq, Dong, Haodi, Lai, Mengyu, Zhou, Xiangmei, Yang, Lifeng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer International Publishing 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398981/
https://ncbi.nlm.nih.gov/pubmed/28083805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-016-0500-0
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