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Identification of Highly Selective MMP-14 Inhibitory Fabs by Deep Sequencing
Matrix metalloproteinase (MMP)-14 is an important target for cancer treatment due to its critical roles in tumor invasion and metastasis. Previous failures of all compound-based broad-spectrum MMP inhibitors in clinical trials suggest that selectivity is the key for a successful therapy. With inhere...
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| Publicado no: | Biotechnol Bioeng |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398909/ https://ncbi.nlm.nih.gov/pubmed/28090632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26248 |
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