GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation

Hepatitis C virus (HCV) infection is a leading cause of chronic liver diseases and hepatocellular carcinoma (HCC) and Golgi protein 73 (GP73) is a serum biomarker for liver diseases and HCC. However, the mechanism underlying GP73 regulates HCV infection is largely unknown. Here, we revealed that GP7...

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Опубликовано в: :PLoS Pathog
Главные авторы: Zhang, Xuewu, Zhu, Chengliang, Wang, Tianci, Jiang, Hui, Ren, Yahui, Zhang, Qi, Wu, Kailang, Liu, Fang, Liu, Yingle, Wu, Jianguo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398727/
https://ncbi.nlm.nih.gov/pubmed/28394926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006321
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