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A Wnt-planar polarity pathway instructs neurite branching by restricting F-actin assembly through endosomal signaling
Spatial arrangement of neurite branching is instructed by both attractive and repulsive cues. Here we show that in C. elegans, the Wnt family of secreted glycoproteins specify neurite branching sites in the PLM mechanosensory neurons. Wnts function through MIG-1/Frizzled and the planar cell polarity...
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| Udgivet i: | PLoS Genet |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398721/ https://ncbi.nlm.nih.gov/pubmed/28384160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006720 |
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