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A Wnt-planar polarity pathway instructs neurite branching by restricting F-actin assembly through endosomal signaling

Spatial arrangement of neurite branching is instructed by both attractive and repulsive cues. Here we show that in C. elegans, the Wnt family of secreted glycoproteins specify neurite branching sites in the PLM mechanosensory neurons. Wnts function through MIG-1/Frizzled and the planar cell polarity...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Chen, Chun-Hao, He, Chun-Wei, Liao, Chien-Po, Pan, Chun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398721/
https://ncbi.nlm.nih.gov/pubmed/28384160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006720
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