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The Complement Anaphylatoxins, C5a and C3a, Suppress Interferon-Beta Production in Response to Listeria monocytogenes by Inhibition of the Cyclic Dinucleotide-Activated Cytosolic Surveillance Pathway

Listeria monocytogenes (Lm) is an intracellular Gram-positive bacterium that induces expression of type I interferons (IFN-α/IFN-β) during infection. These cytokines are detrimental to the host during infection by priming leukocytes to undergo Lm-mediated apoptosis. Our previous studies showed that...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Mueller-Ortiz, Stacey L., Calame, Daniel G., Shenoi, Nancy, Li, Yi-Dong, Wetsel, Rick A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398560/
https://ncbi.nlm.nih.gov/pubmed/28275134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601420
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