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Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites
Cancer cells prefer aerobic glycolysis, but little is known about the underlying mechanism. Recent studies showed that the rate-limiting glycolytic enzymes, pyruvate kinase M2 (PKM2) directly phosphorylates H3 at threonine 11 (H3T11) to regulate gene expression and cell proliferation, revealing its...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398556/ https://ncbi.nlm.nih.gov/pubmed/28426732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175576 |
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