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Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis

PURPOSE: Oct4 was reported to be one of the most important pluripotency transcription factors in the biology of stem cells including cancer stem cells, and progressed malignant cells. Here we report the investigation of gene expression control of Oct4 by selected human microRNAs and the physiologica...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Göhring, Axel R., Reuter, Stefanie, Clement, Joachim H., Cheng, Xinlai, Theobald, Jannick, Wölfl, Stefan, Mrowka, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398498/
https://ncbi.nlm.nih.gov/pubmed/28426762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174912
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