miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells

BACKGROUND: MicroRNAs (miRNAs) are a class of small non-coding RNAs that are strongly involved in various types of carcinogenesis, including hepatocellular carcinoma (HCC). This study aimed to clarify whether miR-4417 promotes HCC growth by targeting TRIM35 and regulating PKM2 phosphorylation. MATER...

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Vydáno v:Med Sci Monit
Hlavní autoři: Song, Lijie, Zhang, Weijie, Chang, Zhiwei, Pan, Yanfeng, Zong, Hong, Fan, Qingxia, Wang, Liuxing
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2017
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398329/
https://ncbi.nlm.nih.gov/pubmed/28394882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.900296
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