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Synthesis of Side-Chain Oxysterols and their Enantiomers through Cross-Metathesis Reactions of Δ(22) Steroids

A synthetic route that utilizes a cross-metathesis reaction with Δ(22) steroids has been developed to prepare sterols with varying C-27 side-chains. Natural sterols containing hydroxyl groups at the 25 and (25R)-26 positions were prepared. Enantiomers of cholesterol and (3β,25R)-26-hydroxycholestero...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Steroids
Hauptverfasser: Brownholland, David P., Covey, Douglas F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398201/
https://ncbi.nlm.nih.gov/pubmed/28300584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2017.03.002
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