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Synthesis of the enantiomer of the oxysterol-antagonist LY295427

Cellular cholesterol homeostasis is regulated by oxygenated cholesterol metabolites called oxysterols. While the importance of oxysterols in the acute regulation of cholesterol homeostasis is known, the precise molecular mechanisms through which oxysterols exert their effects remain to be elucidated...

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Detalhes bibliográficos
Main Authors: Bielska, Agata A., Ory, Daniel S., Covey, Douglas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139699/
https://ncbi.nlm.nih.gov/pubmed/21470559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2011.03.008
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