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Synthesis of the enantiomer of the oxysterol-antagonist LY295427

Cellular cholesterol homeostasis is regulated by oxygenated cholesterol metabolites called oxysterols. While the importance of oxysterols in the acute regulation of cholesterol homeostasis is known, the precise molecular mechanisms through which oxysterols exert their effects remain to be elucidated...

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Bibliografiske detaljer
Main Authors: Bielska, Agata A., Ory, Daniel S., Covey, Douglas F.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139699/
https://ncbi.nlm.nih.gov/pubmed/21470559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2011.03.008
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