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TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids
TBX21 encodes for the transcription factor T-bet (T-box expressed in T cells), which influences naïve T lymphocyte development and has been implicated in asthma pathogenesis. Specifically, the T-bet knockout mouse spontaneously develops airway hyperresponsiveness and other changes consistent with as...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539815/ https://ncbi.nlm.nih.gov/pubmed/15604153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408532102 |
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