TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids

TBX21 encodes for the transcription factor T-bet (T-box expressed in T cells), which influences naïve T lymphocyte development and has been implicated in asthma pathogenesis. Specifically, the T-bet knockout mouse spontaneously develops airway hyperresponsiveness and other changes consistent with as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tantisira, Kelan G., Hwang, Eun Sook, Raby, Benjamin A., Silverman, Eric S., Lake, Stephen L., Richter, Brent G., Peng, Stanford L., Drazen, Jeffrey M., Glimcher, Laurie H., Weiss, Scott T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC539815/
https://ncbi.nlm.nih.gov/pubmed/15604153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408532102
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